pentobarbital will lower the extent or influence of gefitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or outcome of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the extent or influence of propafenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.
pentobarbital will lower the level or influence of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir may very well be diminished if coadministered with powerful CYP3A inducers and is also for that reason contraindicated.
pentobarbital will minimize the extent or result of rolapitant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Prolonged-phrase coadministration of powerful CYP3A4 inducers with rolapitant might substantially lower rolapitant efficacy.
pentobarbital will minimize the extent or influence of felodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Drugs that have step therapy affiliated with Each and every prescription. This restriction generally necessitates that particular requirements be satisfied previous to acceptance with the prescription.
pentobarbital decreases amounts of ponatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Stay away from Unless of course the coadministration outweighs the possible hazard of ponatinib underexposure; keep an eye on for signs of decreased efficacy.
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Barbiturates can result in fetal harm when administered to a Expecting girl; retrospective, situation-managed scientific tests have proposed a connection between maternal intake of barbiturates and an increased-than-anticipated incidence of fetal abnormalities
pentobarbital will reduce the level or influence of eucalyptus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Strong CYP3A4 inducers can lessen panobinostat concentrations by ~70% and lead to therapy failure.
pentobarbital will decrease the extent more info or outcome of ripretinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
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